HAART regimens always need to be individualized for the patient in order to achieve the maximum potency, durability, adherence and tolerability and to avoid longterm toxicities and any likely drug interactions.
It is therefore essential to undertake a full baseline assessment before starting treatment and this should include HIV resistance testing, and screening for hepatitis B and C coinfection. In addition, a full cardiovascular risk assessment should be undertaken and patients should be screened for diabetes and renal problems as well as having a psychosocial history taken to identify psychiatric problems, alcohol use and recreational drug use. In women, it is important to enter into a discussion around plans for pregnancy and the use of contraception.
Articolo presente in – HAART and correlated pathologies n. 9 –